Perspective non-invasive biomarkers: intestinal proteins in the diagnosis for diagnosis and control of intestinal mucosal damage

The aim of this literature review was to consider the diagnostic value potential biomarkers detection: citrulline and intestinal proteins, designed detect mucosa damage. Conclusion : determination I-FABP I-BABP in blood are promising methods for non-invasive diagnosis damage, since these proteins released from damaged enterocytes. However, is important combination with citrulline. Several studies have shown that can be measured animal models, adult pediatric patients. It easily detectable, consistently capable detecting inflammation mucosa. limitation most small sample size. Non-invasive therapeutic monitoring techniques remain an area further research.